Watch Indianapolis Colts vs. Seattle Seahawks live on NBC

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The Seattle Seahawks host the Indianapolis Colts on Sunday Night Football as both teams look to get back to .500.

Russell Wilson will be the focal point of the Seahawks offense after throwing for a career-high 373 yards and four touchdowns in a losing effort vs. the Titans in Week 3. Wilson’s ability to avoid the rush and use his legs will be on full display as Seattle’s offensive line continues to struggle.

On the defensive side, the Seahawks’ “Legion of Boom” will look to get back on track at home in a raucous environment against Colts QB Jacoby Brissett who is filling in for an injured Andrew Luck.

If the Colts have any chance to pull off the upset on the road, Brissett will have to use his legs and connect on some deep throws to T.Y. Hilton.

Football Night in America

Start time: 7:00 p.m. ET

TV channel: NBC

Live stream: NBCSports.com, NBC Sports app

Colts vs. Seahawks

Start time: 8:30 p.m. ET

TV channel: NBC

Live stream: NBCSports.com, NBC Sports app

Packers underdogs, Patriots big favorites among NFL Divisional Round odds

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Aaron Rodgers and the Green Bay Packers thrive as a road underdog in the postseason, but the Dallas Cowboys figure to be healthier and more rested for their showdown on Sunday.

The Cowboys are listed as 4.5-point favorites on the NFL point spreads against the Packers with a 52-point total in their NFC Divisional Round matchup slated for AT&T Stadium on Sunday, according to sportsbooks monitored by OddsShark.com.

Dallas is 1-3 straight-up and 0-4 against the spread in its last four divisional round games, but are also riding a seven-win streak at home where they are 5-2 against the spread.

With Rodgers against Cowboys rookie QB Dak Prescott, the Packers have an edge in experience, and Rodgers’ savvy is reflected in a 6-1 ATS record in their last seven playoff games as an underdog. The Packers, offensively, are almost completely reliant on the passing attack and may have to adapt without WR Jordy Nelson (collapsed lung, ribs).

With the combo of Prescott and RB Ezekiel Elliott, the Cowboys might be able to dictate the pace to a Packers defense that is lacking in pass coverage.

The Atlanta Falcons are listed as 4.5-point favorites against the Seattle Seahawks with a 51.5-point total in the NFC tilt on Saturday. While the Falcons are 1-5 SU and 0-6 ATS in their last six playoff games, the dual threat of WR Julio Jones and Taylor Gabriel means Seahawks CB Richard Sherman will only be able to nullify one receiving threat.

Seahawks QB Russell Wilson will not be facing a statistically-imposing Falcons pass rush, but during their wild card game the Seahawks’ much-maligned offensive line had issues with the Detroit Lions’ garden-variety front four.

The New England Patriots are 16-point favorites against the Houston Texans with a 44.5-point total in the AFC matchup on Saturday. The Patriots, who are 6-2 ATS in their last eight games as a favorite of at least 14 points, won 27-0 in the teams’ regular-season game when third-string QB Jacoby Brissett was playing instead of Tom Brady.

New England also enters the week as the favorites on the odds to win Super Bowl 51, and has a 34.5 percent chance to win the championship according to PredictionMachine.com.

The Kansas City Chiefs are a slim two-point favorite against the Pittsburgh Steelers with a 44.5-point total in Sunday’s AFC betting matchup. The Steelers, with RB Le'Veon Bell and WR Antonio Brown together in the playoffs for the first time, will be trying to break a cycle of being 0-5 SU and 0-4-1 ATS in their last five games on the road after consecutive home games.

Kansas City, 11-2 SU in their last 13 home games, is a changed team since their 29-point road defeat in Pittsburgh in Week 5, with WR Tyreek Hill becoming a touchdown threat to complement QB Alex Smith and TE Travis Kelce.

In the last four years the favored team has only lost SU twice in the Divisional Round (14-2 SU). In the last three years the visiting team is 7-3-2 ATS in the Divisional Round.

Week 16 NFL opening odds have Giants, Raiders, Steelers as favorites

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There is reason to think Eli Manning and the New York Giants will maintain their record of being a near-lock when favored by a field goal or less.

While they’re on the road, the Giants are listed as 2.5-point favorites against the Philadelphia Eagles in the Thursday Night Football matchup at sportsbooks monitored by OddsShark.com.

New York is 6-1-1 against the spread in its last eight games as a favorite of three or fewer points, while the Eagles will be out to break a negative trend of being 0-4 straight-up and ATS in their last four divisional games.

Manning and WR Odell Beckham Jr. are facing an Eagles defense whose yards per pass allowed has ballooned to 7.7, 26th in the 32-team NFL. The Giants’ improving defense could fluster rookie QB Carson Wentz, whose complement of receivers might struggle with getting separation from the trio of Eli Apple, Janoris Jenkins and Dominique Rodgers-Cromartie.

Elsewhere, the Oakland Raiders are 3.5-point favorites against the Indianapolis Colts. Each team’s chances ride heavily on their respective quarterbacks, Andrew Luck and Derek Carr. The status of Colts RT Joe Reitz (back), who would be matched up on pass rusher extraordinaire Khalil Mack, is in doubt. The Raiders are 2-8 ATS in their last 10 home games according to the OddsShark NFL Database.

The Buffalo Bills are 3.5-point favorites against the Miami Dolphins. The Dolphins control their playoff destiny but are 2-9 ATS in their last 11 road games against Buffalo. The Bills’ run defense is a mess and RB Jay Ajayi might be able to provide the necessary support for backup QB Matt Moore, who is coming off a four-touchdown game in Week 15.

The Pittsburgh Steelers are 4.5-point favorites against the Baltimore Ravens in a Christmas Day betting matchup. While Baltimore is on a 7-0 ATS streak in AFC North games, Ravens QB Joe Flacco‘s offense is more sporadic than the unit led by Steelers QB Ben Roethlisberger. The Ravens are 0-7 SU and 1-6 ATS in their last seven games in the late afternoon.

The Kansas City Chiefs are favored by four points against the Denver Broncos in the Sunday Night Football matchup. Although the Chiefs are coming off a loss against Tennessee, they regularly disrupt quarterbacks through DE Chris Jones, OLB Dee Ford and OLB Justin Houston. Denver QB Trevor Siemian and his offensive line haven’t been able to withstand that very often this season.

And the Dallas Cowboys are favored by seven points against the Detroit Lions in the Monday Night Football matchup. Lions QB Matthew Stafford has a chance to put up some points and Detroit’s defense, which allows an average of 98.9 rushing yards, might be able to limit NFL rushing leader Ezekiel Elliott. The Cowboys are not only on an 0-4 ATS streak, but they are 3-10-1 ATS in their last 14 home games against teams with winning records.