NFL Week 7 odds roundup: Vikings, Patriots favorites in marquee matchups

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Sam Bradford had difficulty winning in Philadelphia, and the OddsShark NFL Database shows the same has long been true of the Minnesota Vikings.

The Vikings are listed as 2.5-point favorites against the Philadelphia Eagles for this weekend at sportsbooks monitored by OddsShark.com. The Vikings, who got Bradford from the Eagles after Teddy Bridgewater suffered a major knee injury, are the NFL’s last unbeaten team. They are 3-8 SU in their last 11 games against the Eagles, and 3-10 ATS in their last 13.

The Eagles are 2-6 SU and ATS in their last eight games against teams from the NFC.

Another QB, Brock Osweiler, has a return game in Week 7. The Denver Broncos are seven-point favorites against Osweiler’s Houston Texans for the Monday Night Football game. The Broncos are 7-0 SU and 5-2 ATS in their last seven home games after losing their most recent home game. The Texans are 3-7 ATS in their last 10 games as an underdog of 7.5 or fewer points.

The New England Patriots are favored by seven points against the Pittsburgh Steelers. The Patriots are 11-1 SU in their last 12 October games. The Steelers, who are relying on QB Landry Jones after Ben Roethlisberger was injured during their Week 6 loss in Miami, are 7-1 SU in their last eight games after losing as a favorite.

According to website PredictionMachine.com, going from Roethlisberger to Landry decreases the Steelers’ chances of beating the Patriots from 40.5% to 26.3%.

The Arizona Cardinals are favored by two against the Seattle Seahawks for the Sunday Night Football matchup. The Seahawks are 7-2 SU in their last nine road games. The Cardinals are 3-7 ATS in their last 10 home games.

The Detroit Lions are a one-point favorite against the Washington Redskins. The Lions are 3-8 SU in their last 11 games against teams with winning records. The Redskins are 3-7 ATS in their last 10 games in Week 7.

The Buffalo Bills are favored by three against the rival Miami Dolphins. The Bills are 7-3 ATS in their last 10 games as road favorites. The Dolphins are 2-6 SU in their last eight against teams with winning records.

On Thursday Night Football, the Green Bay Packers are 7.5-point favorites against the Chicago Bears. The Packers are 8-0 SU and 7-1 ATS in their last eight games in Week 7. The Bears are 2-9 SU in their last 11 games against teams with winning records.

The New York Giants are favored by 2.5 points against the Los Angeles Rams entering their game in London. The Giants are 1-5 ATS in their last six games against the NFC West. The Rams are 5-2 SU and ATS in their last seven games as underdogs.

And the Tampa Bay Buccaneers are a road favorite for only the second time since 2011, giving two points against the San Francisco 49ers. The 49ers are 0-5 SU and ATS in their last five games.

Broncos double-digit favorites on Sunday night vs. winless, depleted Giants

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The Denver Broncos head into Sunday night with the largest spread they have had at home after a bye week in at least 25 years. The Broncos are 11.5-point favorites against the winless New York Giants with a 38.5-point total for the Week 6 Sunday Night Football matchup at sportsbooks monitored by OddsShark.com.

Denver is 6-1 straight-up and against the spread in post-bye week games dating back to 2010. There’s a similar long-running trend of Denver being 7-2 SU and ATS in home games following a bye week since 2003. However, this is the first time since 1996 that Denver has been a double-digit favorite in that scenario.

The Giants, which are 0-5 SU and 2-3 ATS, had three wide receivers, including Odell Beckham Jr., sustain season-ending injuries last week. That has left QB Eli Manning with WR Roger Lewis (15 career catches) and WR Tavarres King as his main outside targets. Slot WR Sterling Shephard (sprained ankle) could be inactive.

While team performances tend to gravitate toward the mean with time, the Giants will need to show something new – with replacement-level personnel – in order to move the ball against a Denver pass defense which allows only 6.2 yards per pass, fifth-best in the NFL.

The Broncos’ top-ranked defense, led by OLB Von Miller, is also first in run defense and has every starter healthy. While NFC teams are a combined 1-10 SU on the road against Denver since 2012, the Giants are a solid 7-3 ATS in their last 10 games against the AFC.

Denver, 3-1 SU and 2-1-1 ATS, has been quietly efficient on offense. The Broncos, with QB Trevor Siemian, are in the middle of the NFL pack in yards per pass, but they are facing a Giants secondary that is minus CB Dominique Rodgers-Cromartie (suspension) and has also had inconsistent play from CB Eli Apple.

Denver, 7-2 ATS over its last nine home games in October, has been good at opening holes for the tandem of C.J. Anderson and Jamaal Charles, who are each capable of making things happen in the open field if the tackling gets sloppy. New York also won’t have DT Olivier Vernon drawing double teams up front and keeping blockers off MLB Damon Harrison.

Unless the Broncos stop themselves, they should be able to grind out a workmanlike win.

The total has gone over in three of the Giants’ last four games against the Broncos, according to the OddsShark NFL Database. The total has gone over in six of the Broncos’ last seven games as a favorite of 11.0 points or more.

For more info, picks and a breakdown of this week’s top sports betting news check out the new OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes, or check it out at OddsShark.libsyn.com.

Watch Indianapolis Colts vs. Seattle Seahawks live on NBC

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The Seattle Seahawks host the Indianapolis Colts on Sunday Night Football as both teams look to get back to .500.

Russell Wilson will be the focal point of the Seahawks offense after throwing for a career-high 373 yards and four touchdowns in a losing effort vs. the Titans in Week 3. Wilson’s ability to avoid the rush and use his legs will be on full display as Seattle’s offensive line continues to struggle.

On the defensive side, the Seahawks’ “Legion of Boom” will look to get back on track at home in a raucous environment against Colts QB Jacoby Brissett who is filling in for an injured Andrew Luck.

If the Colts have any chance to pull off the upset on the road, Brissett will have to use his legs and connect on some deep throws to T.Y. Hilton.

Football Night in America

Start time: 7:00 p.m. ET

TV channel: NBC

Live stream: NBCSports.com, NBC Sports app

Colts vs. Seahawks

Start time: 8:30 p.m. ET

TV channel: NBC

Live stream: NBCSports.com, NBC Sports app